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In fact, NO can respond with protein thiols [e.g., groups containing sulfhydryl groups, protein thiol (RSH) or thiolate anion (RS )] to form nitrosothiols (RSNO) groups in a reversible process called S-nitrosylation (64)

The formulations and concepts presented are for general knowledge and experimental understanding

The concentrations of glutathione used in the present study are high

201,202 Administration of the PRMT6 inhibitor EPZO20411 can inhibit the arginine methylation of chromatin condensation regulator 1 (RCC1), block the tyrosine kinase 2 (CK2) -PRMT6-RCC1 signaling axis, inhibit the proliferation of glioblastoma stem cells (GSCs) and increase their sensitivity to radiotherapy